← Back to all trials
Recruiting
NCT07102615
Intracervical Vasopressin
Conditions: Retained Products of Conception
Sex: Female
Ages: 18 Years – 51 Years
Healthy volunteers: No
Phase: PHASE4
Enrollment: 50
Sponsor: Prisma Health-Upstate
Location: The OB/GYN Center Greenville South Carolina
Summary
This randomized study looks at whether using a medicine injected into the cervix of the uterus (intracervical), called vasopressin, helps to achieve better removal of retained products of conception (RPOC). RPOC means that after a pregnancy has ended (through miscarriage, abortion, or delivery), some parts of the pregnancy tissue, usually from the placenta or fetus, have stayed in the uterus. A hysteroscopic removal of RPOC is one type of treatment. This is a surgical procedure where a doctor uses a small camera attached to a thin tube (called a hysteroscope) to look inside the uterus.
The main goal of the study is :
• To add to the existing research through this study to see if the injection of intracervical vasopressin leads to improved completion rates of hysteroscopic management of RPOC.
Participants will:
• would be randomized to receive either vasopressin intracervical injection or a placebo injection (non-active saline) during your procedure. Information from the procedure will be collected from the participant's medical record.
Eligibility Criteria
Inclusion Criteria:
* Women
* Aged 18-51
* Undergoing surgical management for retained products of conception, postpartum retained products of conception or 1st trimester missed or incomplete abortion
Exclusion Criteria:
* Hemodynamic instability
* Active hemorrhage- soaking pad/hour
* Allergy to vasopressin
* Concern for intrauterine arteriovenous malformation
* Inability to consent
Source: ClinicalTrials.gov (NCT07102615). StuddyBuddy aggregates publicly available trial information.