The Intervention of Lactobacillus Plantarum Probiotics in Adult Autistic Spectrum Disorders

This is a qualitative and quantitative mixed-methods, open-label study, will involve 12 participants and their caregivers. Participants will also undergo blood exams and gait analysis, while caregivers will complete qualitative interviews and quantitative questionnaires on autistic symptoms, stress, anxiety, and quality of life. After the baseline assessments, participants will receive Lactobacillus plantarum for 8 weeks, followed by further evaluations at end point.

Inclusion Criteria: * Those who have been diagnosed with autistic spectrum disorder aged 18\~50 years old * Those whose primary contacts or caregiver (including family members or teachers) are willing to participate * Those whose primary contacts or caregivers can understand Mandarin and can answer relevant questions or questionnaires. Exclusion Criteria: * Have taken antibiotics or are receiving antibiotic treatment within one month. * Have used probiotic products in powder, capsule or tablet form within two weeks (excluding yogurt, Yakult and other related foods). * Patients who have undergone hepatobiliary gastrointestinal surgery (except for colorectal polypectomy and appendectomy). * Past or current patients with inflammatory bowel disease. * Those with a history of cancer. * Those who are allergic to lactic acid bacteria products. * Those who are receiving parenteral nutrition. * Those who are evaluated by the principal investigator to be unsuitable to participate in the research.