Remote Intervention to Prevent Overdose

This Type 1 hybrid effectiveness-implementation randomized controlled trial, A Remote Intervention to Prevent Overdose among People who Use Stimulants and/or Opioids, aims to address the United States opioid crisis driven by fentanyl and other synthetic opioids by reducing overdose rates. It is supported by and included in the HEAL Initiative. This study would be the first national, fully remote trial to assess the impact of remote education on overdose outcomes, using a novel 2x2 design crossing remote education with remote access support. This research will inform scalability around remote education programs to address the nation's opioid overdose crisis.

Inclusion Criteria: * 18 years old * English-speaking and reading * Report using illicit opioids and/or stimulants (including counterfeit pills) within the past 3 months per the ASSIST * Able and willing to provide informed consent * Be able and willing to provide the names and contact information of three close contacts to reach if the participant cannot be reached Exclusion Criteria: * Living in a restricted environment (e.g., prison)