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NCT07163858
Postural Mobilization Compared to Noradrenaline Only in Off-Pump CABG Surgery
Conditions: Coronary Artery Disease With Need for Bypass Surgery, Coronary Artery Disease(CAD), Coronary Artery Bypass, Off Pump Coronary Artery Bypass Graft, Off Pump Coronary Artery Bypass Surgery, Hemodynamic Management, Hemodynamic Optimization, Noradrenaline
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 50
Sponsor: Infirmerie Protestante de Lyon
Location: Infirmerie Protestante de Lyon Caluire-et-Cuire Auvergne-Rhône-Alpes
Summary
This interventional prospective randomized study is designed to compare hemodynamic management using postural mobilization (+/- noradrenaline) versus noradrenaline only in patients undergoing open-heart coronary artery bypass graft (CABG) surgery.
Eligibility Criteria
Inclusion Criteria:
* Adult patient
* patient requiring isolated coronary bypass surgery
* Elective procedure or medical emergency
* First cardiac surgery
* Patient with an EF ≥30%
* Mandatory affiliation to a social security system
* Signed informed consent form
* Suspension of renin-angiotensin system inhibitors and angiontensn-neprilysin receptor blockers and sartans the day before surgical procedure
Exclusion Criteria:
* Contraindication to an inotropic substance (only NA will be used)
* Contraindication to passive leg raising
* Patient in a life-threatening emergency
* History of cardiac surgery
* Bilateral iliac or common femoral artery occlusion
* EF \< 30%
* Pregnancy and breastfeeding
* Renal failure (GFR \< 40 ml/min/1.73 m²)
* Patient with bilateral thigh amputation
* Class III obesity BMI \> 40 kg/m²
Source: ClinicalTrials.gov (NCT07163858). StuddyBuddy aggregates publicly available trial information.
