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Recruiting
NCT07169825
Evaluation of Targeted Radionuclide Therapy of Lu-177 PSMA in Patients With Compromised Renal and/or Bone Marrow Function
Conditions: Lu-177 PSMA
Sex: Male
Healthy volunteers: No
Phase: PHASE4
Enrollment: 25
Sponsor: M.D. Anderson Cancer Center
Location: MD Anderson Cancer Center Houston Texas
Summary
To determine the dose of Pluvicto therapy absorbed in the tumors and organs of patients whose kidneys and/or bone marrow are not working properly.
Eligibility Criteria
Eligibility Criteria
* Participants that are approved for Pluvicto therapy and have been identified to have renal complications or compromised marrow function. Renal complication is defined as GFR: 30-50ml/min, creatinine: ULN-twofold ULN; while compromised marrow function is indicated by total WBC 2.5 x 109 L - LLN, or platelet count 75-100 x 109 L.
* Participants who agree to be imaged multiple times as defined in the study protocol.
Exclusion Criteria
* Pluvicto therapy patients without renal or marrow function complications
* Participants who do not wish to be imaged multiple times as per the study protocol.
* Women and children since this is treatment for prostate cancer.
Source: ClinicalTrials.gov (NCT07169825). StuddyBuddy aggregates publicly available trial information.