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Enrolling By Invitation
NCT07179458
Criterion-learning Naming Treatment For Addressing Comprehension Deficits in Aphasia
Conditions: Aphasia
Sex: All
Ages: 18 Years – 89 Years
Healthy volunteers: No
Phase: NA
Enrollment: 20
Sponsor: Albert Einstein Healthcare Network
Location: Jefferson Moss Rehabilitation Research Institute Elkins Park Pennsylvania
Summary
Aphasia is a disorder of spoken and written language, most commonly following a stroke. It is estimated that between 2.5 and 4 million Americans are living with aphasia today. A common problem in aphasia involves difficulty retrieving known words in the course of language production and comprehension. The overarching goal of this project is to develop and test early efficacy, efficiency, and the tolerability of a lexical treatment for aphasia in multiple-session regimens that are comprised of retrieval practice, distributed practice, and training dedicated to the elicitation of correct retrievals. The aim of this work is to add to and refine the evidence base for the implementation and optimization of these elements in the treatment of production and comprehension deficits in aphasia, and make important steps towards an ultimate goal of self-administered lexical treatment grounded in retrieval practice principles (RPP) to supplement traditional speech-language therapy that is appropriate for People with Aphasia (PWA) from a broad level of severity of lexical processing deficit in naming and/or comprehension. This project cumulatively builds on prior work to develop a theory of learning for lexical processing impairment in aphasia that aims to ultimately explain why and for whom familiar lexical treatments work, and how to maximize the benefits they confer.
Eligibility Criteria
Inclusion Criteria:
* English as a native or primary language
* Adults with stroke who are at least 6 months post-onset
* Exhibit semantic comprehension deficit, defined as a minimum of 80 errors on word-picture verification pre-test
Exclusion Criteria:
* History of comorbid neurological diagnoses, such as Multiple Sclerosis or Parkinson's Disease
* History of a learning disability that significantly impacted language development, such as developmental language disorder
* Insufficient stamina to participate in the protocol
Source: ClinicalTrials.gov (NCT07179458). StuddyBuddy aggregates publicly available trial information.