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Active Not Recruiting NCT07182838

Proof-of-Concept Clinical Pharmacology Trial for HIV Antigen Presentation Therapeutic Biologic Mix

Conditions: HIV Infections

Sex: All
Ages: 24 Years – 64 Years
Healthy volunteers: No
Phase: EARLY_PHASE1
Enrollment: 20
Sponsor: Han Xu, M.D., Ph.D., FAPCR, Medical Director, IRB Chair

Location: Medicine Invention Design Incorporation - IORG0007849 - NPI 1023387701 Rockville Maryland

Summary

Conducting an initial small, controlled clinical pharmacology trial to assess for therapeutic biologics activity (proof-of-concept) that suggests the potential for clinical benefit of HIV (+) patients 1. Treat Infection of Multiple Gene Mutation HIV Virus Strains. 2. Activate Human Antigen Presentation Reaction to HIV Specific Antigen. 3. The human antigen presenting cells (APCs) can take up and process HIV target antigen protein into small peptide fragments, and then HIV virus can be killed by APCs directly.

Eligibility Criteria

* Conducting an initial small, controlled trial to assess therapeutic biologics activity (proof-of-concept) that suggests the potential for clinical benefit of HIV (+) patients. * 20 HIV (+) patients Inclusion Criteria: * HIV Positive * Positive testing by standard RT-PCR assay or equivalent testing * No AIDS Symptoms * No clinical signs indicative of Severe or Critical Illness Severity * Sign Informed Consent Form Exclusion Criteria: * Severe or Critical Illness Severity * Pregnancy * Breast-feeding * The patients with other serious inter-current illness * Serious Allergy * Serious Bleed or Clot Tendency * Serious side-effects of the biological product * The prohibition of the biological product

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07182838). StuddyBuddy aggregates publicly available trial information.