← Back to all trials
Active Not Recruiting
NCT07182838
Proof-of-Concept Clinical Pharmacology Trial for HIV Antigen Presentation Therapeutic Biologic Mix
Conditions: HIV Infections
Sex: All
Ages: 24 Years – 64 Years
Healthy volunteers: No
Phase: EARLY_PHASE1
Enrollment: 20
Sponsor: Han Xu, M.D., Ph.D., FAPCR, Medical Director, IRB Chair
Location: Medicine Invention Design Incorporation - IORG0007849 - NPI 1023387701 Rockville Maryland
Summary
Conducting an initial small, controlled clinical pharmacology trial to assess for therapeutic biologics activity (proof-of-concept) that suggests the potential for clinical benefit of HIV (+) patients
1. Treat Infection of Multiple Gene Mutation HIV Virus Strains.
2. Activate Human Antigen Presentation Reaction to HIV Specific Antigen.
3. The human antigen presenting cells (APCs) can take up and process HIV target antigen protein into small peptide fragments, and then HIV virus can be killed by APCs directly.
Eligibility Criteria
* Conducting an initial small, controlled trial to assess therapeutic biologics activity (proof-of-concept) that suggests the potential for clinical benefit of HIV (+) patients.
* 20 HIV (+) patients
Inclusion Criteria:
* HIV Positive
* Positive testing by standard RT-PCR assay or equivalent testing
* No AIDS Symptoms
* No clinical signs indicative of Severe or Critical Illness Severity
* Sign Informed Consent Form
Exclusion Criteria:
* Severe or Critical Illness Severity
* Pregnancy
* Breast-feeding
* The patients with other serious inter-current illness
* Serious Allergy
* Serious Bleed or Clot Tendency
* Serious side-effects of the biological product
* The prohibition of the biological product
Source: ClinicalTrials.gov (NCT07182838). StuddyBuddy aggregates publicly available trial information.