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Completed
NCT07185321
A Phase 1 Study of Mosliciguat in Healthy, Adult Males
Conditions: Healthy Volunteer
Sex: Male
Ages: 18 Years – 50 Years
Healthy volunteers: Yes
Phase: PHASE1
Enrollment: 8
Sponsor: Pulmovant, Inc.
Location: Pharmaron Baltimore Maryland
Summary
This is a single-center, Phase 1, open-label, 3-period, fixed-sequence study to investigate the bioavailability, absorption, metabolism, excretion and the safety of mosliciguat administered to healthy male adults.
Eligibility Criteria
Inclusion Criteria:
* Participants willing and able to provide informed consent.
* Considered to be in good health by the Investigator, as determined by medical history, physical examination, vital sign measurements, 12 lead electrocardiogram (ECG), and laboratory test results.
Exclusion Criteria:
* History or presence of any condition (e.g., chronic diarrhea, urinary incontinence), or prior surgery (e.g., gastric bypass) that, in the opinion of the Investigator, poses a significant risk to participant safety and/or achievement of study objectives
* History or presence of COPD, moderate or persistent asthma, other chronic lung disease, or chronic respiratory condition within the last 5 years
* Acute or recent respiratory infection symptoms not resolved at least 3 days prior to Period 1 check-in.
Source: ClinicalTrials.gov (NCT07185321). StuddyBuddy aggregates publicly available trial information.