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Recruiting
NCT07224789
Liquid Biopsy for Early Detection of Colorectal Cancer Using Circular RNA
Conditions: Colorectal Cancer
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: Yes
Enrollment: 600
Sponsor: City of Hope Medical Center
Location: City of Hope Medical Center Duarte California
Summary
Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. This study aims to develop a non-invasive liquid biopsy assay using plasma-derived cell-free circular RNAs (cf-circRNAs) for early and accurate detection of colorectal cancer.
Eligibility Criteria
Inclusion Criteria:
* Adults (≥18 years old)
* Histologically confirmed colorectal cancer (Stage I-III)
* Availability of pre-treatment plasma samples
* Written informed consent provided
Exclusion Criteria:
* History of other active malignancies within the past 5 years
* Poor sample quality or hemolysis
* Inability to provide informed consent
Source: ClinicalTrials.gov (NCT07224789). StuddyBuddy aggregates publicly available trial information.