Join us at Health Research Day — June 6th at Canton Waterfront Park, Baltimore!   Learn More →
← Back to all trials
Enrolling By Invitation NCT07228065

Fixed-Dose Combinations Pragmatic Randomized Implementation Trial for Blood Pressure Control

Conditions: Hypertension, Primary Care

Sex: All
Ages: 18 Years – 80 Years
Healthy volunteers: No
Phase: NA
Enrollment: 720
Sponsor: Brigham and Women's Hospital

Location: Advocate Health Milwaukee Wisconsin

Summary

The proposed study is an effectiveness-implementation hybrid type II trial designed to evaluate the impact of provider- and patient-directed interventions on FDC use. The trial will test the effectiveness of theory-driven nudges tailored to address provider and patient barriers. All interventions will be pharmacist-driven, with pharmacists delivering information via nudges to providers and via nudges or more intensive interventions (i.e., CPA) to patients. Data to evaluate outcomes will be extracted from electronic health records.

Eligibility Criteria

Inclusion Criteria: * patients with documented hypertension diagnosis * had an elevated ambulatory blood pressure reading during the qualifying visit (systolic \>140 mmHg or diastolic \>90 mmHg * have an upcoming scheduled visit * have an active prescription for 1 blood pressure lowering medication with a fixed-dose combination (FDC) alternative Exclusion Criteria: * have received a prescription for a FDC in the preceding two years * reside in a nursing home * have a documented allergy to any FDC components * are pregnant * preferred language is not English or Spanish, defined as documentation in the EHR indicating a primary language other than English or Spanish, or a documented request for an interpreter in a language other than Spanish * have a diagnosis of heart failure or renal failure, given that antihypertensive management in these populations typically requires disease-specific regimens and more frequent treatment adjustments

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07228065). StuddyBuddy aggregates publicly available trial information.