Geriatric Oncology Assessment and Coping Skills Training for Older Women on Aromatase Inhibitor Therapy

Conditions: Breast Cancer, Hormone Receptor Positive, Aromatase Inhibitor-Associated Arthralgia

Sex: Female

Ages: 65 Years – N/A

Healthy volunteers: No

Phase: NA

Enrollment: 452

Sponsor: Duke University

Summary

Older women (≥65 years) with HR+ non-metastatic breast cancer experience high symptom burden and reduced quality of life during aromatase inhibitor (AI) therapy. This hierarchical 2×2 factorial randomized controlled trial will test two interventions: (1) a clinic-level geriatric oncology assessment and support program (GOAL-AI) and (2) a patient-level CBT-based coping skills training (CST-AI). The study aims to improve pain, symptom burden, and health-related quality of life compared to enhanced usual care.

Eligibility Criteria

Inclusion Criteria: * Female, age ≥65 years * HR+ non-metastatic breast cancer * Within 12 months of starting AI therapy * English-speaking * Able to provide consent Exclusion Criteria: * Age \

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07232056). StuddyBuddy aggregates publicly available trial information.