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Active Not Recruiting
NCT07244770
The Effects of Some Antihyperglycemic Drugs on Cognitive Function and Risk of Depression of Diabetic Patients
Conditions: MCI
Sex: All
Ages: 55 Years – N/A
Healthy volunteers: No
Enrollment: 300
Sponsor: Beni-Suef University
Location: Beni Suef Hospital Banī Suwayf
Summary
The study aims to investigate the effects of DPP-4 Is+ metformin versus SGLT2 Is + metformin on the risk of cognitive decline and depression in patients with T2DM.
Eligibility Criteria
Inclusion Criteria:
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The study participants should meet the following inclusion criteria:
1. T2DM adult subjects (\>55 years old) will be eligible to participate.
2. Patients should be taking SGLT2Is+metformin or DDP4Is + metformin for at least 1 year to be eligible.
Exclusion Criteria:
1- Those with type1 diabetes or ketoacidosis, insulin therapy, end organ failure as chronic renal failure, liver, and heart failure, previous history of pancreatitis, history of Alzheimer's disease or any brain insult, and finally pregnant or lactating females will be excluded from the study.
Source: ClinicalTrials.gov (NCT07244770). StuddyBuddy aggregates publicly available trial information.
