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Recruiting
NCT07246525
Intermittent Preventive Treatment of Malaria in School-age Children to Decrease Community Transmission
Conditions: Malaria
Sex: All
Ages: N/A – 17 Years
Healthy volunteers: Yes
Phase: PHASE4
Enrollment: 4800
Sponsor: University of California, San Francisco
Location: Infectious Diseases Research Collaboration Kampala
Summary
The CRITICal study aims to estimate the effectiveness of intermittent preventive treatment in school children (IPTsc) with dihydroartemisinin-piperaquine (DP) for reducing community level malaria burden. Given that school-aged children are the primary drivers of transmission, the study hypothesis is that IPTsc will reduce this infectious reservoir and thus the burden of malaria in persons of all ages in surrounding communities.
Eligibility Criteria
Inclusion Criteria:
* Child currently attending the participating school.
* Agreement of parent/guardian to provide informed consent.
* Agreement of children aged 8-17 years to provide assent.
Exclusion Criteria:
* Missing school on three consecutive days of the school survey.
Source: ClinicalTrials.gov (NCT07246525). StuddyBuddy aggregates publicly available trial information.
