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Recruiting NCT07286032

A Study to Evaluate the Efficacy and Safety of Hetrombopag Olamine Tablets Vs Placebo in Patients With Chemotherapy-Induced Thrombocytopenia

Conditions: Patients With Chemotherapy-Induced Thrombocytopenia

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: PHASE3
Enrollment: 150
Sponsor: Jiangsu HengRui Medicine Co., Ltd.

Location: Cancer and Blood Specialty Clinic Los Alamitos California

Summary

The study is being conducted to evaluate the efficacy, and safety of of Hetrombopag Olamine Tablets Vs Placebo in Patients with Chemotherapy-Induced Thrombocytopenia.

Eligibility Criteria

Inclusion Criteria: 1. Male or female gender, age ≥18 years at screening. 2. Histologically or cytologically confirmed solid tumor (e.g., non-small-cell lung carcinoma \[NSCLC\], breast, ovarian, bladder, pancreatic, gastrointestinal, or colon/colorectal cancer). 3. Receiving platinum- and/or gemcitabine-containing chemotherapy regimens on 21-day treatment cycles. 4. Eastern Cooperative Oncology Group performance status (ECOG PS) 0-2. 5. Life expectancy ≥6 months. 6. Signed ICF for voluntary participation in the study and good compliance. Exclusion Criteria: 1. Hematopoietic diseases other than CIT (e.g., primary immune thrombocytopenia). 2. Hematologic malignancies. 3. Thrombocytopenia caused by reasons other than chemotherapy, including but not limited to chronic liver disease, hypersplenism, infection, and hemorrhage, within 6 months prior to Study Day 1. 4. Untreated brain metastases; or with leptomeningeal metastasis. 5. Conditions that require emergent treatment (e.g., superior vena cava syndrome, spinal cord compression). 6. Severe cardiovascular disorders or interventions within 6 months 7. Have arterial/venous thrombosis within 6 months 8. Known bleeding disorders, platelet dysfunction 9. Severe haemorrhage during screening 10. Acute or uncontrolled hepatitis B\&C infection 11. Human immunodeficiency virus (HIV) infection.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07286032). StuddyBuddy aggregates publicly available trial information.