Effect of Sevoflurane vs Desflurane on Mechanical Power in Laparoscopic Cholecystectomy

Sex: All

Ages: 18 Years – 65 Years

Healthy volunteers: No

Phase: NA

Enrollment: 138

Sponsor: Konya City Hospital

Summary

This single-center, prospective, randomized, assessor-blinded clinical trial aims to compare the effects of sevoflurane and desflurane anesthesia on intraoperative mechanical power in adult patients undergoing elective laparoscopic cholecystectomy. Mechanical power will be measured at three standardized time points using a validated formula, and secondary outcomes include driving pressure values and early postoperative respiratory complications (desaturation, laryngospasm, bronchospasm, cough).

Eligibility Criteria

Inclusion Criteria: * Adults aged 18-65 years ASA Physical Status I-II Scheduled for elective laparoscopic cholecystectomy Able to provide written informed consent Exclusion Criteria: Known hypersensitivity or contraindication to study medications (sevoflurane or desflurane) Severe chronic obstructive pulmonary disease (COPD) Uncontrolled bronchial asthma Decompensated heart failure (NYHA Class III-IV) History of prior lung surgery Morbid obesity (BMI \> 35 kg/m²) Pregnancy Refusal to participate or inability to provide informed consent \-

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07295158). StuddyBuddy aggregates publicly available trial information.