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Completed
NCT07350109
Investigation of Sedation Depth Via BIS Monitoring in ICU After Cardiac Surgery
Conditions: Sedation After Cardiac Surgery
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 50
Sponsor: Medical University of Graz
Location: Medical University Graz Graz Styria
Summary
This study is a non-interventional, observational research project focused on monitoring sedation levels in patients who have undergone cardiac surgery. It uses a tool called Bispectral Index (BIS), which measures brain activity to assess sedation depth. The goal is to understand how often patients experience deep sedation (BIS \
Eligibility Criteria
Inclusion Criteria:
* Age ≥ 18 years.
* Undergoing cardiac surgery with subsequent admission to the ICU
* expected duration of invasive mechanical ventilation \> 6 hours postop.
* Written informed consent obtained from the patient or legal representative (if the patient is not capable of consent).
Exclusion Criteria:
* Pre-existing neurological disorders affecting consciousness or sedation assessment (e.g., severe dementia, epileptic encephalopathy).
* Acute neurological events in the perioperative period (e.g., stroke, intracranial hemorrhage).
* Severe hepatic dysfunction (Child-Pugh Class C).
* Participation in another interventional study potentially affecting sedation or cognitive outcomes.
* Pregnancy or lactation.
* Patients in whom short-term survival is deemed unlikely due to clinical course
Source: ClinicalTrials.gov (NCT07350109). StuddyBuddy aggregates publicly available trial information.