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Completed
NCT07413133
A Study to Assess How the Body Absorbs ABBV-8736 Subcutaneous Injections Relative to Intravenous Injections in Adult Healthy Volunteers
Conditions: Healthy Volunteer
Sex: All
Ages: 18 Years – 60 Years
Healthy volunteers: Yes
Phase: PHASE1
Enrollment: 40
Sponsor: AbbVie
Location: CenExel ACT- Anaheim Clinical Trials /ID# 280481 Anaheim California
Summary
The purpose of this study is to assess the pharmacokinetics (PK), bioavailability, immunogenicity, safety, and tolerability of ABBV-8736 following subcutaneous (SC) administration relative to intravenous (IV) administration.
Eligibility Criteria
Inclusion Criteria:
* Body mass index (BMI) is \>= 18.0 to \= 35 kg.
* A condition of general good health, based upon the results of a medical history, physical examination, vital signs, laboratory profile and a 12-lead electrocardiogram (ECG).
Exclusion Criteria:
* Participant requires any over-the-counter and/or prescription medication, vitamins, and/or herbal supplements, on a regular basis.
* Participant uses any medications, vitamins and/or herbal supplements within the 14-day period prior to study treatment administration.
* Participant has received any treatment by injection within 30 days or within a period defined by 5 half-lives, whichever is longer, prior to study treatment administration.
* Participant has prior exposure to a Triggering Receptor Expressed on Myeloid Cells 1 (TREM1) agent.
Source: ClinicalTrials.gov (NCT07413133). StuddyBuddy aggregates publicly available trial information.