Aerobic Training in Lower Extremity Lymphedema

This randomized controlled study aims to evaluate the effects of aerobic exercise training on gait, postural control, lower extremity muscle strength, and functional status in individuals with bilateral lower extremity lymphedema. A total of 24 participants aged between 20 and 60 years with a diagnosis of bilateral lower extremity lymphedema will be randomly assigned to either an aerobic exercise group or a control group. The aerobic exercise group will receive aerobic exercise training in addition to Complex Decongestive Therapy (CDT), while the control group will receive CDT alone. Lower extremity edema will be assessed using circumferential measurements taken from the ankle to the inguinal region. Gait function will be evaluated through angular and spatiotemporal analysis using Kinovea software, including parameters such as step length, walking speed, and double support time. Postural control will be assessed using the Balance Error Scoring System (BESS) and the Timed Up and Go Test. Lower extremity muscle strength and endurance will be evaluated using Manual Muscle Testing and the 30-Second Sit-to-Stand Test. Functional status of the lower extremities will be assessed using the Lower Extremity Functional Scale (LEFS).

Inclusion Criteria: * Aged between 20 and 60 years * Diagnosed with bilateral lower extremity lymphedema * Completion of chemotherapy, radiotherapy, or other oncological treatments, with no oncological contraindication to participation * Signed written informed consent * Willingness to participate in the study Exclusion Criteria: * Presence of uncontrolled cardiac or pulmonary disease * Presence of renal insufficiency * Presence of musculoskeletal or neurological disorders affecting mobility or balance * Presence of systemic or local infection in the lower extremity * Impaired independent ambulation or use of assistive walking devices * Pregnancy * Presence of visual, cognitive, or intellectual impairment that may interfere with participation in assessment or intervention procedures