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Recruiting
NCT07432477
Single-step vs Stepwise Lung Recruitment Maneuvers After Cardiopulmonary Bypass
Conditions: Atelectasis, Postoperative
Sex: All
Ages: 18 Years – 80 Years
Healthy volunteers: No
Phase: NA
Enrollment: 52
Sponsor: Ondokuz Mayıs University
Location: Ondokuz Mayıs University, Faculty of Medicine Samsun
Summary
This prospective randomized controlled trial aims to compare the hemodynamic and pulmonary effects of single-step and stepwise lung recruitment maneuvers in adult patients undergoing elective cardiac surgery with cardiopulmonary bypass. After separation from cardiopulmonary bypass, patients will be randomized to receive either a single-step sustained inflation recruitment maneuver or a stepwise incremental recruitment maneuver, both combined with 8 cmH₂O positive end-expiratory pressure. The primary outcome is the change in cardiac index before and after the recruitment maneuver. Secondary outcomes include lung ultrasound atelectasis score, and hemodynamic parameters.
Eligibility Criteria
Inclusion Criteria:
* Age 18-80 years
* ASA (American Society of Anesthesiologists) II-IV
* Patients undergoing elective cardiac surgery (coronary artery bypass grafting, mitral valve replacement, aortic valve replacement)
Exclusion Criteria:
* Emergency surgery
* Presence of perioperative arrhythmia
* \50 mmHg systolic pulmonary artery pressure
* Known chronic obstructive pulmonary disease or interstitial lung disease
* Pneumothorax
* Mean arterial pressure \
Source: ClinicalTrials.gov (NCT07432477). StuddyBuddy aggregates publicly available trial information.