Nifedipine Extended-Release in Patients With Mild or Moderate Hypertension

To evaluate the efficacy of Nifedipine 30mg Extended-Release Richmond versus Nifedipine 30mg extended-release with a current registration in Colombia, measured by the proportion of patients with controlled blood pressure in adult patients diagnosed with mild or moderate hypertension at week 8 of follow-up.

Inclusion Criteria: * Men or women aged 18 years or older * Confirmed diagnosis of mild-to-moderate primary hypertension according to ESC/ESH Guidelines (12), with blood pressure readings of systolic blood pressure (SBP) \< 140 mmHg or diastolic blood pressure (DBP) \< 90 mmHg * Patient with controlled blood pressure readings during the last 4 weeks of enrollment, verified by medical records, according to ESC/ESH Guidelines (12). * Use of nifedipine as monotherapy is preferred, or in combination therapy according to clinical judgment (maintaining the combination throughout the study without changing the nifedipine dose or the doses of concomitant medications the patient is currently taking). * Voluntary participation with written informed consent. Exclusion Criteria: * Contraindication for Nifedipine use according to the established safety profile (as per the literature - Investigator's Manual): * History of documented hypertensive encephalopathy in the medical record * Evidence of secondary hypertension such as coarctation of the aorta, pheochromocytoma, hyperaldosteronism (except hypothyroidism/controlled hyperthyroidism), and obstructive sleep apnea * History of a diagnosis or condition that, in the investigator's judgment, may affect patient safety. • History of severe allergies to any medication * Subject with heart failure, New York Heart Association (NYHA) class III or IV * Severe coronary artery disease manifested by a history of myocardial infarction or unstable angina within the 6 months prior to visit 1 * Valvular heart disease "Valvular heart disease with symptoms (dyspnea, syncope, or chest pain) documented in current medical history" * History of malignancy within the past 5 years, excluding skin or basal cell carcinoma * Surgical or medical conditions that may alter the metabolism, excretion, or distribution or absorption of any drug. * Gastrointestinal disease or surgery that may result in malabsorption. * Severe narrowing of the gastrointestinal tract; Kock bag (ileostomy after proctocolectomy). * Cholestasis or biliary obstruction, or history of pancreatic injury, or clinically significant elevation of lipase, amylase, or bilirubin. * Transaminase levels (AST and ALT) \> 3 x ULN. * Renal insufficiency, defined as eGFR \