The Impact of Dupilumab Treatment on Anxiety and Depression Symptoms in Patients With Moderate-to-Severe Atopic Dermatitis

This study aims to assess the impact of dupilumab on the mental health and quality of life of moderate-to-severe Atopic Dermatitis (AD) patients. The study will recruit participants from AD patients who are already receiving dupilumab treatment. The study enrollment period will be about 9 months with each of the participants undergoing a 6-month observational study period.

Inclusion Criteria: * Participants who have moderate to severe AD with signs and symptoms of anxiety and/or depression. * Participants who initiate dupilumab therapy within 30 days of enrolment, based on the treating physician's decision, independently of study participation * Participants and/or their legally approved representatives (LAR in case of the minor subject) must agree to sign an informed consent or an assent. Exclusion Criteria: * Females who are pregnant, lactating, or planning/intending to be pregnant in the next 6 months. * Participants who are participating in another trial. * Participants with active chronic or acute infection requiring systemic treatment. * Participants who are diagnosed with active endoparasite infection or are suspected of being at high risk of infection. * Participants with human immunodeficiency virus (HIV), hepatitis B or C, malignancy, or other concomitant illnesses. * Participants on antidepressants/anti-anxiety within 6 months of enrolment or those who are planning to receive antidepressants/anti-anxiety. In addition, those who will use antidepressants/anti-anxiety medications throughout the study will be excluded from the analysis. The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.