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Enrolling By Invitation
NCT07483164
A Study Of T1/Tref Intubating Conditions
Conditions: Intubation
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 108
Sponsor: Mayo Clinic
Location: Mayo Clinic in Florida Jacksonville Florida
Summary
The purpose of this study is to determine the maximum ratio of the twitch amplitude (T1) to the reference twitch (Tref) amplitude (T1/Tref) that provides excellent intubating conditions.
Eligibility Criteria
Inclusion Criteria:
* Age \> or = 18 years old
* Patients willing to participate and provide an integrated, informed consent
Exclusion Criteria
* Patients with disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture, or any similar wrist injury.
* Patients with systemic neuromuscular diseases such as myasthenia gravis.
* Patients with significant organ dysfunction that can significantly affect pharmacokinetics of neuromuscular blocking and reversal agents, i.e., severe renal impairment requiring dialysis or end-stage liver disease.
* Patients requiring a rapid sequence induction for airway protection.
* Patients deemed ineligible for surgery, including pregnancy (as determined by standard of care testing).
Source: ClinicalTrials.gov (NCT07483164). StuddyBuddy aggregates publicly available trial information.