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NCT07506512
Optimal Time Interval Between Mifepristone and Misoprostol Administration for Early Pregnancy Loss
Conditions: Early Pregnancy Loss
Sex: Female
Healthy volunteers: No
Phase: PHASE3
Enrollment: 1000
Sponsor: University of Pennsylvania
Summary
A prospective cohort study to explore the optimal time interval between mifepristone and misoprostol administration for medical management of early pregnancy loss. Participants will be followed to assess treatment success, satisfaction, and side effects.
Eligibility Criteria
Inclusion Criteria:
* Able to participate in the informed consent process and provide a signed and dated consent form.
* Stated willingness to comply with all study procedures.
* Access to device with text or email capability.
* Able to read and understand English.
* Confirmed diagnosis of intrauterine embryonic/fetal demise or anembryonic gestation (ultrasound examination demonstrates a fetal pole without cardiac activity measuring between 5.3 and 40mm or an abnormal growth pattern diagnostic of early pregnancy loss.
Exclusion Criteria:
* Incomplete or inevitable abortion.
* Contraindication or allergy to mifepristone or misoprostol
* Unable to return for clinic-based follow-up.
Source: ClinicalTrials.gov (NCT07506512). StuddyBuddy aggregates publicly available trial information.