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Completed NCT07532330

Tyrosine Vs Tacrolimus With NB-UVB in Vitiligo

Conditions: Vitiligo

Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: No
Phase: NA
Enrollment: 67
Sponsor: Minia University

Location: Minia Tertiary University Hospital, Faculty of Medicine, Minia University, Minia, Egypt. Minya Minya Governorate

Summary

The goal of this clinical trial is to learn if adding topical tacrolimus or topical tyrosine to narrowband UVB phototherapy works to treat vitiligo in adults. It will also learn about the safety of both combinations. The main questions it aims to answer are: Which combination (UVB + tacrolimus or UVB + tyrosine) leads to greater skin repigmentation (color return) after 3 months of treatment? What side effects do participants experience with each combination? Researchers will compare three groups: UVB + tacrolimus, UVB + tyrosine, and UVB only to see which is more effective and safer. Participants will: Receive narrowband UVB phototherapy sessions two times per week at minimal erythema dose Apply either topical tacrolimus or topical tyrosine to their vitiligo patches twice daily Visit the clinic every one month for skin examination and photography Report any side effects or skin reactions

Eligibility Criteria

Inclusion Criteria: * Patients aged 18-65 years with vitiligo who are candidates for narrowband UVB (NB-UVB) phototherapy. Exclusion Criteria: * Pregnant or lactating women. * Patients who have received any systemic or topical treatment for vitiligo within the preceding three months.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07532330). StuddyBuddy aggregates publicly available trial information.