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Completed
NCT07537270
Neural Mobilization vs Cervical Neuromodulation in DPN
Conditions: Diabetic Peripheral Neuropathy Type 2
Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: No
Phase: NA
Enrollment: 75
Sponsor: Abeer Abdrabo
Location: Cairo University Hospitals, Kasr Al-Ainy Cairo
Summary
This study is a three-arm, assessor-blinded, randomized controlled pilot feasibility trial. The primary goal is to evaluate the feasibility and acceptability of conducting a full-scale randomized controlled trial (RCT) comparing two manual therapy techniques: Manual Neural Mobilization (MNM) and Cervical Neuromodulatory Intervention (CNI) in individuals with Diabetic Peripheral Neuropathy (DPN).
While glycemic control is a central part of managing type 2 diabetes, this study explores whether non-pharmacological manual therapies can serve as adjunctive interventions to improve metabolic outcomes. A total of 75 participants were assigned to either MNM, CNI, or standard care for 12 weeks. The study focuses on recruitment rates, adherence, and safety, while also exploring secondary outcomes like blood glucose levels (HbA1c, FBG) .
Eligibility Criteria
Inclusion Criteria:
* Clinically confirmed diabetic peripheral neuropathy
* Ability to attend twice-weekly intervention sessions for 12 weeks
* Stable medication regimen for at least 3 months
Exclusion Criteria:
* Severe cardiovascular, neurological, or musculoskeletal disorders
* Recent surgery (\
Source: ClinicalTrials.gov (NCT07537270). StuddyBuddy aggregates publicly available trial information.