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NCT07538544
MCE Molecular Imaging for Myocarditis
Conditions: Myocarditis Acute
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: EARLY_PHASE1
Enrollment: 30
Sponsor: University of Virginia
Location: University of Virginia Charlottesville Virginia
Summary
Inflammation of the heart (myocarditis) is a serious condition that can cause heart failure, abnormal heart rhythms, cardiac arrest, and death. Rapid diagnosis of this condition is key to reversing it. The purpose of this study is to determine whether myocarditis such as that which occurs with viral illness, autoimmune conditions, or certain therapies (i.e. immune checkpoint inhibitors) can be diagnosed using a new form of ultrasound imaging of the heart (echocardiography) that uses a contrast agent that is targeted to inflammation (Sonazoid).
Eligibility Criteria
Inclusion Criteria:
* Age ≥18 years of age
* At least two of the following manifestations of myocarditis:
1. new or suspected new high-sensitivity troponin \>3 times upper limit of normal
2. new or suspected new LV dysfunction with LVEF \
Source: ClinicalTrials.gov (NCT07538544). StuddyBuddy aggregates publicly available trial information.