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NCT07581860
Growth Hormone Resistance of Beta-cells
Conditions: Healthy, Obesity & Overweight, Impaired Fasting Glucose (IFG), Impaired Glucose Tolerance (Prediabetes)
Sex: All
Ages: 18 Years – 59 Years
Healthy volunteers: Yes
Enrollment: 10
Sponsor: University of Missouri-Columbia
Location: University of Missouri School of Medicine Columbia Missouri
Summary
The purpose of the research study is to better understand how beta-cells (cells in the pancreas that make insulin and help regulate blood sugar) respond to growth hormone in people with impaired fasting glucose or impaired glucose tolerance at the University of Missouri. The aim of the study is to advance understanding of how growth hormone affects beta-cells and risk factors for developing type 2 diabetes.
Eligibility Criteria
Inclusion Criteria:
* body mass index \>18.5kg/m2 and \/= 100mg/dL, \2 cigarettes per day
* greater than 3% weight loss within three months of screening or engaged in regular (\>/= 3 days per week), continuous moderate- or high-intensity exercise of \>/= 30 min duration
* mentally disabled persons, prisoners, and persons with inability to grant voluntary informed consent
Source: ClinicalTrials.gov (NCT07581860). StuddyBuddy aggregates publicly available trial information.
