← Back to all trials
Recruiting
NCT07583251
Safety And Tolerability Of Gamma Glutamylcysteine (GGC) Oral Supplementation In MCI Patients
Conditions: Mild Cognitive Impairment (MCI)
Sex: All
Ages: 55 Years – 80 Years
Healthy volunteers: No
Phase: PHASE1
Enrollment: 9
Sponsor: Pravat Mandal
Location: UPMC Presbyterian Hospital Pittsburgh Pennsylvania
Summary
The goal of this study is to evaluate the safety and tolerability of Gamma Glutamylcysteine (GGC) supplement at different doses (400mg/day or 800mg/day or 1200mg/day) when administered orally to patients with MCI over 3 months. This study is designed to generate preliminary clinical safety data to inform the feasibility and design of larger controlled trials.
Eligibility Criteria
Inclusion Criteria:
1. Memory complaints;
2. MCI diagnosis
3. MoCA score between 18-25
4. Age 55 - 80 years old.
5. Ability to read and write in English
Exclusion Criteria:
1. Subjects with a history of cancer;
2. Subjects with a history of schizophrenia, manic-depressive disorder
3. Subjects on antioxidant therapy (ashwagandha, gingko biloba, N-acetylcysteine or glutathione)
4. Subjects on illicit drug (cocaine, heroin, marijuana, or fentanyl) abuse/dependence;
Source: ClinicalTrials.gov (NCT07583251). StuddyBuddy aggregates publicly available trial information.