A Wearable Biosensor Patch for Non-Invasive Monitoring for Patients Undergoing Abdominal or Chest Surgery

This clinical trial tests the feasibility and safety of a wearable biosensor patch for non-invasive monitoring for patients undergoing abdominal or chest surgery. Wearable biosensor patches have been developed by researchers to provide a non-invasive way to monitor substances that are normally checked using blood tests. This may reduce the need for frequent blood draws. The patches use gentle electrical stimulation to produce sweat and tiny built-in sensors to measure substances such as glucose, creatinine, and markers of inflammation, as well as oxygen and carbon dioxide levels. The wearable biosensor patch may be a feasible and safe way to monitor patients undergoing abdominal or chest surgery.

Inclusion Criteria: * Age ≥ 18 years * Scheduled to have an elective abdominal or thoracic operation with anticipated post-operative hospitalization ≥ 3 days * Willingness to provide sweat samples, complete surveys, and permit review of medical records for research use * Ability to consent to the study procedures Exclusion Criteria: * Carbachol or pilocarpine allergy * Adhesive/tape allergy * Damaged or irritated skin on one or both wrists that prohibits placement of the biosensor and sweat collecting devices * Pregnant women * Children less than 18 years of age