Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix

This investigator-initiated study will compare ADM and resorbable cross-linked collagen membrane barriers for guided bone regeneration at atrophic lateral ridge augmentation sites.

Inclusion Criteria: * English speaking * At least 18 years old * Must be a patient of the UAB Dental School * Able to read and understand informed consent document * Patients presenting with a diagnosed need horizontal ridge augmentation with GBR without simultaneous implant placement, to allow for future dental implant placement. * Presence of periodontally healthy, non-carious neighboring teeth and/or healthy restored dental implants on either side of the edentulous span planned for GBR, or unhealthy adjacent teeth to be extracted during the same visit. * ≤4 mm ridge width in a Seibert Class I Edentulous span19 * No anticipated need for surgical and/or endodontic care at planned teeth adjacent to the proposed surgical site during the study period. Exclusion Criteria: * Non-English speaking * Less than 18 years old * Smokers/nicotine users (defined as currently reporting use of any form of tobacco/nicotine products) * Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing, including: * Uncontrolled diabetes (HbA1c \> 7%) * Untreated periodontal disease * History of head/neck radiation * IV bisphosphonates * Immunocompromised state * Pregnancy * Acute infection at site * Documented or suspected allergy or sensitivity to any study product