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NCT07623590
Titration of Positive End-expiratory Pressure: Comparison Between Manual Thoracic or Abdominal Compression and Electrical Impedance Tomography
Conditions: ARDS (Acute Respiratory Distress Syndrome)
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 30
Sponsor: Centre Hospitalier Saint Joseph Saint Luc de Lyon
Location: GHU Henri Mondor Créteil
Summary
Patients with acute respiratory distress syndrome are placed on mechanical ventilation, and the adjustment of ventilator parameters is an important step in their care, in particular positive expiratory pressure, applied at the end of breathing.
The goal of this study is to learn if continuous anterior chest compression works as well as electrical impedance tomography for positive expiratory pressure titration.
Researchers will compare the two methods for each patient, in a randomly determined order : continuous anterior chest compression and electrical impedance tomography.
Participants will :
* have a pep titration with both techniques
* be included in the study for 28 days
Eligibility Criteria
Inclusion Criteria:
* Age ≥ 18 years
* Moderate to severe ARDS according to the Berlin criteria
* Patient receiving sedation and continuous curarization
* Free and informed consent from the patient or their loved one
Exclusion Criteria:
* ECMO
* Pneumothorax
* Chest trauma in the last 3 months
* Uncontrolled shock (noradrenaline \> 5 mg/h)
* Pregnant or breastfeeding woman
* Protected adult within the meaning of the law
* Lack of social security
* Patient under AME
Source: ClinicalTrials.gov (NCT07623590). StuddyBuddy aggregates publicly available trial information.
