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NCT07633002
The Application of HCG in Luteal Support for Frozen Embryo Transfer in Ovulation Cycle of Obese Women
Conditions: Obesity, Maternal
Sex: Female
Ages: 22 Years – 37 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 750
Sponsor: The Second Hospital of Shandong University
Summary
This study aims to explore whether the application of low-dose HCG in luteal support can improve the pregnancy outcomes of natural cycle frozen embryo transfer in obese patients
Eligibility Criteria
Inclusion Criteria:
* Age ≤37 years old ② Prepare the endometrium in the natural cycle/ovulation induction cycle ③ BMI≥24 according to the overweight standard for the Asian population ④ Single blastocyst transfer (including IVF and ICSI-assisted pregnancy) ⑤ At least one frozen blastocyst remaining in the IVF/ICSI cycle with a Gardner morphology score of ≥4BC, and the age of the frozen embryo is D5 or D6
Exclusion Criteria:
* There is a history of adenomyosis, hydrosalpinx, intrauterine adhesions or untreated submucosal fibroids of the uterus
* Uterine malformations; ③ The endometrial thickness on the conversion day is less than 7mm, or the cycle was cancelled during the endometrial preparation process before frozen embryo transfer due to the endometrium being less than 7mm in the past.
* Have a history of the immune system, such as antiphospholipid syndrome/systemic lupus erythematosus/rheumatism; ⑤ Diabetic patients who have not been controlled by standardized medication; ⑥ Those who have undergone embryo transfer more than or equal to two times without achieving a live birth ⑦ Those whose embryos to be thawed and thawed are from donated or frozen egg sources, or have undergone two freezing operations
Source: ClinicalTrials.gov (NCT07633002). StuddyBuddy aggregates publicly available trial information.