Home-based Vision Rehabilitation Guided by Brain Imaging

Conditions: Visual Field Defect, Stroke, Hemianopia Homonymous, Quadrantanopia, Cortical Blindness, Visual Field Defect, Peripheral, Visual Field Loss, Traumatic Brain Injury, Brain Tumor

Sex: All

Ages: 18 Years – N/A

Healthy volunteers: No

Phase: NA

Enrollment: 100

Sponsor: Georgetown University

Location: Georgetown University Medical Center Washington D.C. District of Columbia

Summary

The BRIGHT (Behavioral Rehabilitation Through Image-Guided Home-based Training) study aims to evaluate the effectiveness of image-guided, home-based perceptual training at improving visual performance in individuals with visual field loss. Using a prospective, crossover design, BRIGHT combines visual behavioral testing, neuroimaging, and a home-based intervention. It aims to 1) identify neural pathways that support training-induced visual plasticity; and 2) compare the efficacy of different types of visual training delivered in a home-based setting.

Eligibility Criteria

Inclusion Criteria: 1. At least 18 years of age. 2. Capable of providing informed consent and complying with study procedures. 3. Unilateral or bilateral focal brain damage causing visual field loss. 4. At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year. 5. Eligible for MRI based on standard safety screening. Exclusion Criteria: 1. Severe neurological or psychiatric conditions unrelated to the focal lesion that may interfere with study participation or data interpretation. 2. Current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5. 3. Ocular disease or disorder.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07635329). StuddyBuddy aggregates publicly available trial information.