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NCT07637526
Study to Evaluate Efficacy and Safety of Belantamab-based Combinations for Relapsed Multiple Myeloma
Conditions: Relapse Multiple Myeloma
Sex: All
Ages: 18 Years – N/A
Enrollment: 100
Sponsor: PETHEMA Foundation
Summary
The goal of this retrospective observational study is to characterize multiple myeloma (MM) patients (by collecting demographics, disease characteristics and treatment history data) treated in first or second relapse with belantamab mafodotin combinations under compassionate use conditions.
The main question it aims to answer is which belantamab combinations (belantamab mafodotin+bortezomib+dexamethasone \[BVd\] vs. belantamab mafodotin+pomalidomide+dexamethasone \[BPd\]) show higher response rates in patients with MM in first or second relapse.
Eligibility Criteria
Inclusion Criteria:
* Confirmed diagnosis of relaps/refractory MM.
* Having received at least one dose of a belantamab mafodotin combination (BVd or BPd) under compassionate use conditions as treatment for a first or second relapse.
* Patients ≥18 years of age at the start of treatment with the belantamab mafodotin combination (BVd or BPd) under compassionate use conditions.
Exclusion Criteria:
* Any patient who has received a belantamab mafodotin combination (BVd or BPd) under compassionate use conditions in fourth line of treatment or later will be excluded from the study.
Source: ClinicalTrials.gov (NCT07637526). StuddyBuddy aggregates publicly available trial information.