A Study to Compare Safety of 4 Weeks Exposure to Propellants Hydrofluoroalkane 1,1-difluoroethane (HFA-152a) and HFA-1,1,1,2-tetrafluoroethane (134a)

This study aims to generate additional safety data on the propellant component of the reformulated product by comparing metered dose inhaler (MDIs) containing HFA-152a (test) with HFA-134a (reference).

Inclusion Criteria: * Participant must be aged greater than equal to (\>=)18 years at the time of signing the informed consent. * Participants with asthma for \>= 6 months, defined as: * Documented history of asthma, as defined by Global Initiative for Asthma (GINA) * Receiving one of following asthma treatments for at least 12 weeks prior to the screening visit and which is anticipated to remain stable for the duration of the study: * Short-Acting beta2-Adrenoreceptor Agonists (SABA) as needed (prn) only * Inhaled corticosteroid (ICS)/SABA prn only * SABA prn plus ICS prn * SABA prn plus ICS maintenance * ICS/SABA prn plus ICS maintenance * SABA prn plus ICS/ Long-acting beta agonist (LABA) maintenance * ICS/SABA prn plus ICS/LABA maintenance * SABA prn plus ICS/ Long-acting muscarinic antagonist (LAMA)/LABA maintenance (open or closed triple therapy) * ICS/Formoterol combination therapy as reliever therapy * ICS/Formoterol combination therapy as maintenance therapy plus ICS/Formoterol combination as reliever therapy. * Leukotriene receptor antagonist (LTRA) as add-on any of the above is permitted * Xanthines as add-on to any of the above permitted * Biological therapies indicated for the treatment of asthma as add-on to any of the above are permitted (for example, but not limited to, mepolizumab, dupilumab, tezepelumab). * Participants with severity of disease: * Baseline pre-bronchodilator Forced expiratory volume in 1 second (FEV1) \>=50 percent (%) of predicted at screening. * Asthma Control Status * Asthma Control Questionnaire (ACQ)-6 score less than (\1.5 times ULN if direct bilirubin is \480 milliseconds (msec).