← Back to all trials
Not Yet Recruiting
NCT07650487
Perioperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Grafting: A Prospective Clinical Study
Conditions: Myocardial Injury, Coronary Artery Disease
Sex: All
Ages: 21 Years – 80 Years
Healthy volunteers: No
Enrollment: 150
Sponsor: Second Hospital of Jilin University
Location: the Second Hospital of Jilin University Changchun Jilin
Summary
Perioperative myocardial injury (PMI) following coronary artery bypass grafting (CABG) is associated with postoperative morbidity, mortality, and long-term outcomes. High-sensitivity troponin assays and cardiac MRI offer reliable diagnostic tools for PMI, but evidence regarding optimal diagnostic thresholds and perioperative imaging strategy is limited. This prospective clinical study aims to determine the incidence of perioperative myocardial injury using multimodal assessments including high-sensitivity troponin, electrocardiogram, echocardiography, cardiac MRI, and perioperative cardiovascular events.
Eligibility Criteria
Inclusion Criteria:
1. Age ≥ 21 years
2. Undergoing CABG for unstable angina
3. Able to provide written informed consent
4. No major cardiovascular event in the prior 6 months
Exclusion Criteria:
1. Significant hepatic, renal, or other major organ dysfunction
2. Pregnancy or breastfeeding
3. Withdrawal during the study
4. Contraindication to cardiac MRI (metal implants, claustrophobia, etc.)
Source: ClinicalTrials.gov (NCT07650487). StuddyBuddy aggregates publicly available trial information.