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Not Yet Recruiting NCT07650487

Perioperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Grafting: A Prospective Clinical Study

Conditions: Myocardial Injury, Coronary Artery Disease

Sex: All
Ages: 21 Years – 80 Years
Healthy volunteers: No
Enrollment: 150
Sponsor: Second Hospital of Jilin University

Location: the Second Hospital of Jilin University Changchun Jilin

Summary

Perioperative myocardial injury (PMI) following coronary artery bypass grafting (CABG) is associated with postoperative morbidity, mortality, and long-term outcomes. High-sensitivity troponin assays and cardiac MRI offer reliable diagnostic tools for PMI, but evidence regarding optimal diagnostic thresholds and perioperative imaging strategy is limited. This prospective clinical study aims to determine the incidence of perioperative myocardial injury using multimodal assessments including high-sensitivity troponin, electrocardiogram, echocardiography, cardiac MRI, and perioperative cardiovascular events.

Eligibility Criteria

Inclusion Criteria: 1. Age ≥ 21 years 2. Undergoing CABG for unstable angina 3. Able to provide written informed consent 4. No major cardiovascular event in the prior 6 months Exclusion Criteria: 1. Significant hepatic, renal, or other major organ dysfunction 2. Pregnancy or breastfeeding 3. Withdrawal during the study 4. Contraindication to cardiac MRI (metal implants, claustrophobia, etc.)

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07650487). StuddyBuddy aggregates publicly available trial information.