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Recruiting
NCT07652970
Tele-CE in Severe Stroke
Conditions: Stroke
Sex: All
Ages: 18 Years – 80 Years
Healthy volunteers: No
Phase: NA
Enrollment: 40
Sponsor: University of Illinois at Chicago
Location: Brain Plasticity Lab Chicago Illinois
Summary
The goal of this clinical trial is to determine the effects of home-based cross-education on lower limb neuroplasticity in severe stroke.
The main questions the investigators aim to answer are:
* What are the effects of home-based cross-education on lower limb neuroplasticity?
* What are the effects of home-based cross-education on lower limb function?
* Is home-based cross-education feasible to administer and accepted by participants?
Participants will take part in ten home-based, remotely supervised sessions, during which participants will either perform unilateral skill and strength training of the unaffected lower limb (Tele-Cross Education or Tele-CE) or cognitive training and unilateral movements of the unaffected lower limb (Tele-control). Each participant will experience measures of brain and spinal activity and motor function testing before and after both sessions (Tele-CE and Tele-control). Each participant will also be asked to fill out a feedback questionnaire to assess acceptability after intervention sessions (Tele-CE and Tele-control).
Eligibility Criteria
Inclusion Criteria:
* Single, monohemispheric stroke
* Chronic stroke (\> 6 months prior)
* Severe stroke (Fugl-Meyer Lower Extremity motor scale score \< 21 or 6 Minute Walk Test distance \< 300m)
Exclusion Criteria:
* Use of anti-spasticity medications
* Existence of other neurological disorders
* Have brainstem or cerebellar lesions.
* Mini-Mental State Examiniation score of \
Source: ClinicalTrials.gov (NCT07652970). StuddyBuddy aggregates publicly available trial information.