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NCT07663019
Chatbot Intervention Effects on Belief Updating in Anhedonia
Conditions: Healthy
Sex: All
Ages: 18 Years – 40 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 80
Sponsor: University of Electronic Science and Technology of China
Location: University of Electronic Science and Technology of China Chengdu Sichuan
Summary
The main aim of the present study is to investigate the effects of a Motivational Interviewing-based artificial intelligence chatbot on belief updating in college students with elevated levels of depression and anhedonia by combining a randomized active-control intervention design with pre- and post-intervention behavioral belief updating task assessments.
Eligibility Criteria
Inclusion Criteria:
* 18-40 years
* Right-handed
* Normal or corrected normal visual acuity
* Participants must show elevated anhedonia and depressive symptoms at screening, defined as a total score of 22 or higher on the Snaith-Hamilton Pleasure Scale and a score of 14 or higher on the Beck Depression Inventory
Exclusion Criteria:
* History of major central nervous system disorders, such as epilepsy, traumatic brain injury, stroke, or brain tumors.
* History of severe mental illness, including schizophrenia spectrum disorders, bipolar disorder, or other psychotic disorders.
* History of substance or alcohol use disorder or substance or alcohol misuse within the past 12 months that may affect study participation or outcome assessment.
* Individuals currently at high risk of suicide, severe self-harm, or experiencing an acute psychiatric crisis.
* Individuals who are currently using psychiatric medications or have undergone psychotherapy within the past 4 weeks that may significantly affect mood, motivation, or reward processing.
* Severe vision or hearing impairments that cannot be corrected and would interfere with task performance.
* Contraindications to MRI scanning, including metallic implants, pacemakers, severe claustrophobia, or other conditions incompatible with MRI.
* Pregnancy or breastfeeding.
Source: ClinicalTrials.gov (NCT07663019). StuddyBuddy aggregates publicly available trial information.