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Not Yet Recruiting NCT07668505

Anti-inflammation Treatment for Idiopathic Inflammatory Myopathies

Conditions: Myositis

Sex: All
Ages: 18 Years – 80 Years
Healthy volunteers: No
Phase: PHASE4
Enrollment: 10
Sponsor: Chinese University of Hong Kong

Location: Prince of Wales hospital Hong Kong

Summary

The goal of this clinical trial is to learn if the drug Maraviroc works to treat refractory idiopathic inflammatory myopathy (myositis) in patients who have not responded well to traditional therapies. It will also learn about how the drug affects muscle inflammation and function. The main questions it aims to answer are: Does Maraviroc reduce inflammation in the muscles? Does Maraviroc improve patients' muscle function and overall clinical symptoms? This is an open-label study, meaning researchers will give Maraviroc to all participants (there is no placebo) to see if the drug works to treat refractory myositis. Participants will: Take a 300mg Maraviroc tablet every day for 12 weeks Undergo exams and tests with their doctors to check their muscle function, symptom improvement, and specific health markers (like enzyme levels)

Eligibility Criteria

Inclusion Criteria: 1. ≥18 to \18 years 3. fulfillment of 2017 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) IIM classification criteria 4. active myositis defined as Manual Muscle Testing 8 (MMT8) score \

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07668505). StuddyBuddy aggregates publicly available trial information.