← Back to all trials
Not Yet Recruiting
NCT07673549
Efficacy and Safety of Oral Antiviral Therapy for Idiopathic Trigeminal Neuralgia
Conditions: Idiopathic Trigeminal Neuralgia
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 165
Sponsor: Beijing Tiantan Hospital
Summary
This is a multicenter, prospective, randomized, controlled trial. A total of 165 patients with idiopathic trigeminal neuralgia will be enrolled and randomly divided into three groups at a 1:1:1 ratio. The aim is to compare the efficacy and safety of conventional carbamazepine monotherapy, carbamazepine combined with oral antiviral therapy, and carbamazepine combined with anti-inflammatory therapy in pain relief, quality of life improvement and adverse event profiles.
Eligibility Criteria
Inclusion Criteria:
1. Diagnosed with idiopathic trigeminal neuralgia according to standard clinical criteria.
2. No secondary etiology confirmed by cranial imaging.
3. No severe systemic disease or immune system disease.
4. Voluntary participation and signed informed consent.
Exclusion Criteria:
1. Secondary trigeminal neuralgia of any cause.
2. Active herpes zoster infection recently.
3. Severe hepatic or renal insufficiency or contraindications to study drugs.
4. Unable to complete questionnaire evaluation independently.
5. Pregnancy or lactation state. -
Source: ClinicalTrials.gov (NCT07673549). StuddyBuddy aggregates publicly available trial information.
