← Back to all trials
Recruiting
NCT07673601
A Study to Assess the Absolute Bioavailability and How Adimanebart SC Moves Through the Body in Healthy Adult Participants
Conditions: Healthy Volunteers (HV), Healthy Volunteer
Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: Yes
Phase: PHASE1
Enrollment: 52
Sponsor: argenx
Location: Altasciences Montreal
Summary
This study aims to find out how much adimanebart gets into the blood circulation of healthy adults. Researchers will measure the amount of adimanebart in blood over time to learn how it moves through the body. The drug's safety will also be assessed.
The participants will be assigned to one of 3 parts of the study: part 1 investigates the absolute bioavailability; part 2 investigates the effect of different body weights on adimanebart in blood after subcutaneous (SC) dosing; part 3 investigates formulation adaptations.
Participants will be in the study for approximately up to 24 weeks.
Eligibility Criteria
Inclusion Criteria:
* Is at least the local legal age of consent and aged 18 to 65 years, inclusive, when signing the ICF.
* Has a body weight between 60 and 100 kg and a BMI between 18.5 and 30 kg/m2, inclusive, at screening and on day -1 for part 1 and part 3, or has a body weight \
Source: ClinicalTrials.gov (NCT07673601). StuddyBuddy aggregates publicly available trial information.
