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Completed
NCT07678476
Brisk Walking and Baduanjin Improve Inhibitory Function in Older Adults With Cognitive Impairment
Conditions: Cognition Impairment
Sex: All
Ages: 60 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 45
Sponsor: Shanghai University of Sport
Location: Shanghai University of Sport Shanghai
Summary
This study aims to investigate the acute effects of single-session different forms of aerobic exercise (brisk walking and Baduanjin) on inhibitory function and resting-state EEG power in older adults with cognitive impairment, providing scientific evidence for developing exercise intervention programs for this population.
Specifically, this study seeks to answer the following core questions:
1. Can a single session of brisk walking and a single session of Baduanjin exercise improve reaction time and accuracy on the Stroop color-word task in older adults with cognitive impairment?
2. Are there differential effects on inhibitory function between the two exercise modalities?
3. Does a single exercise session induce immediate changes in resting-state EEG power spectrum across multiple frequency bands (δ, θ, α, β)?
4. Are changes in resting-state EEG power associated with improvements in inhibitory function?
Forty-five older adults with cognitive impairment will be randomly assigned to three groups (n=15 each): brisk walking group, Baduanjin group, and control group (quiet seated rest). Participants in the brisk walking and Baduanjin groups will each perform a single 30-minute moderate-intensity exercise session. All participants will complete the Stroop color-word task (assessing reaction time and accuracy under both congruent and incongruent conditions) and undergo a 5-minute eyes-closed resting-state EEG recording before and immediately after the intervention.
Eligibility Criteria
Inclusion Criteria:
* Age ≥ 60 years, regardless of gender;
* Right-handed;
* Montreal Cognitive Assessment (MoCA) score ≤ 25;
* Normal or corrected-to-normal vision;
* Normal hearing;
* Signed informed consent.
Exclusion Criteria:
* Presence of severe cognitive impairment or other neurodegenerative diseases;
* Presence of psychiatric disorders, or current or long-term use of psychotropic medications;
* Presence of severe cardiovascular diseases (e.g., heart failure, atherosclerosis, myocardial infarction, etc.);
* Presence of severe muscle diseases, or a history of lower limb injury within the past six months that would preclude the ability to stand for extended periods.
Source: ClinicalTrials.gov (NCT07678476). StuddyBuddy aggregates publicly available trial information.