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Completed NCT07678476

Brisk Walking and Baduanjin Improve Inhibitory Function in Older Adults With Cognitive Impairment

Conditions: Cognition Impairment

Sex: All
Ages: 60 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 45
Sponsor: Shanghai University of Sport

Location: Shanghai University of Sport Shanghai

Summary

This study aims to investigate the acute effects of single-session different forms of aerobic exercise (brisk walking and Baduanjin) on inhibitory function and resting-state EEG power in older adults with cognitive impairment, providing scientific evidence for developing exercise intervention programs for this population. Specifically, this study seeks to answer the following core questions: 1. Can a single session of brisk walking and a single session of Baduanjin exercise improve reaction time and accuracy on the Stroop color-word task in older adults with cognitive impairment? 2. Are there differential effects on inhibitory function between the two exercise modalities? 3. Does a single exercise session induce immediate changes in resting-state EEG power spectrum across multiple frequency bands (δ, θ, α, β)? 4. Are changes in resting-state EEG power associated with improvements in inhibitory function? Forty-five older adults with cognitive impairment will be randomly assigned to three groups (n=15 each): brisk walking group, Baduanjin group, and control group (quiet seated rest). Participants in the brisk walking and Baduanjin groups will each perform a single 30-minute moderate-intensity exercise session. All participants will complete the Stroop color-word task (assessing reaction time and accuracy under both congruent and incongruent conditions) and undergo a 5-minute eyes-closed resting-state EEG recording before and immediately after the intervention.

Eligibility Criteria

Inclusion Criteria: * Age ≥ 60 years, regardless of gender; * Right-handed; * Montreal Cognitive Assessment (MoCA) score ≤ 25; * Normal or corrected-to-normal vision; * Normal hearing; * Signed informed consent. Exclusion Criteria: * Presence of severe cognitive impairment or other neurodegenerative diseases; * Presence of psychiatric disorders, or current or long-term use of psychotropic medications; * Presence of severe cardiovascular diseases (e.g., heart failure, atherosclerosis, myocardial infarction, etc.); * Presence of severe muscle diseases, or a history of lower limb injury within the past six months that would preclude the ability to stand for extended periods.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07678476). StuddyBuddy aggregates publicly available trial information.