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NCT07679828
Polypills Approach for Multiple Cardiovascular Risk Factors
Conditions: Hypertension, Dyslipidemia, Diabetes
Sex: All
Ages: 50 Years – 75 Years
Healthy volunteers: No
Phase: NA
Enrollment: 8252
Sponsor: China Medical University, China
Location: Affiliated Hospital of Chifeng University Chifeng Inner Mongolia
Summary
The Polypill Approach for Multiple Cardiovascular Risk Factors (PACIF) trial is a multicenter randomized controlled trial that will test the effectiveness and safety of a fixed-dose combination strategy for integrated management of hypertension, dyslipidemia, and diabetes among adults aged 50 to 75 years in China. The trial will evaluate whether a simplified regimen combining blood pressure-lowering, lipid-lowering, and glucose-lowering therapy improves the 10-year cardiovascular disease risk score at phase 1. Participants will be followed to determine whether the fixed-dose combination strategy reduces major cardiovascular events and cognitive function compared with usual care at phase 2.
Eligibility Criteria
Inclusion Criteria:
* Men or women
* Age ≥50 years and \
Source: ClinicalTrials.gov (NCT07679828). StuddyBuddy aggregates publicly available trial information.
