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NCT07680179
Peer Delivered Youth Suicide Prevention in Nepal
Conditions: Suicide, Suicide Prevention
Sex: All
Ages: 12 Years – 24 Years
Healthy volunteers: No
Phase: NA
Enrollment: 160
Sponsor: Yale University
Location: Sochai Nepal Makwanpur
Summary
South Asia has the highest suicide rate in the world with important risk profile differences from high-income settings. Investigators will conduct formative research to co-design a package of brief interventions and implementation strategies to prevent youth-suicide and then test the package in a pilot feasibility hybrid type 2 cluster randomized controlled trial in Nepal. Potential health impacts may be substantial as results can be applied not only in similar South Asian primary healthcare contexts, but also in low-resource settings in the US and abroad, where the suicide burden remains high.
Using experience-based co-design and equity-focused implementation frameworks, this study will assess the feasibility and acceptability of a Youth-focused, Peer-delivered, Family-engaged Suicide Prevention Package (YPF-SuPP) integrated within existing mhGAP services in Nepal's decentralized primary healthcare system. This pilot trial will generate preliminary data to inform the design of a future fully powered effectiveness trial and potential scale-up of youth suicide prevention strategies.
Eligibility Criteria
Inclusion Criteria:
Peer Volunteers
* Age ≥18 years
* No current untreated mental disorder or suicide risk, as assessed and confirmed by a Nepali mental health specialist (MD or PhD)
* Meets hiring and eligibility criteria of the local implementing partner NGO
* Fluent in spoken Nepali
Trial Youth Patient Participants
* Age 12-24 years
* Resident of the study site
* Screens positive to the Nepali Ask Suicide Screening Questions or a lifetime history of a suicide attempt
* Ability to provide informed consent or assent
* For participants under 18 years of age, written informed consent from a legal guardian
* Fluent in Nepali
Family Members (intervention group only)
* Family member (defined as any individual that is a parent, grandparent, aunt/uncle, or cousin as well as significant others) selected by the youth participants enrolled in the study
* Resident of the study site
* Over 18 years of age
* Ability to provide informed consent or assent
* Fluent in Nepali
Exclusion Criteria:
Peer Volunteers
* Plans to leave the peer volunteer role within the next 6 months
* Unable to provide voluntary informed consent for any reason
Trial Youth Patient Participants
* Requires immediate psychiatric hospitalization at the time of assessment
* Unable to provide informed consent or assent due to impaired decision-making capacity
* Participants under 18 years of age without written informed consent from a legal guardian
* Planning to leave the study area in the next 6 months
Family Members
* Requires immediate psychiatric hospitalization at the time of assessment
* Unable to provide informed consent or assent due to impaired decision-making capacity
* Planning to leave the study area in the next 6 months
Source: ClinicalTrials.gov (NCT07680179). StuddyBuddy aggregates publicly available trial information.