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NCT07683650
Hyaluronic Acid and I-PRF Mixture for TMJ Disc Displacement Management
Conditions: TMJ Disc Displacement With Reduction
Sex: All
Ages: 18 Years – 45 Years
Healthy volunteers: No
Phase: NA
Enrollment: 72
Sponsor: Mansoura University
Location: Faculty of Dentistry Mansoura University Al Mansurah
Summary
The aim of this study is to evaluate the efficacy of hyaluronic acid and I-PRF mixture for intra-articular injection following arthrocentesis in the management of TMJ reducible disc displacement.
Eligibility Criteria
Inclusion Criteria:
1. Age: 18 - 45 years.
2. Patients with disc displacement with reduction in any of the TMJs.
3. arthralgia.
4. Limited unassisted mouth opening.
5. Co-operative patients.
Exclusion Criteria:
1. Patients with previous history of TMJ minimally invasive interventions.
2. Patients with autoimmune or connective tissue diseases affecting the joints.
3. Patients with neurological disorders.
4. Patients with a history of condylar fractures or ankylosis.
5. Patients with psychological problems.
6. Patients receiving non-steroidal anti-inflammatory drugs within 48 hours preoperatively, or systemic use of corticosteroids within 2 weeks.
7. Patients on anticoagulants, suffering from platelet function disorders or fibrinogen deficiency.
8. Patients with moderate to severe myogenic pain.
Source: ClinicalTrials.gov (NCT07683650). StuddyBuddy aggregates publicly available trial information.
