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NCT07685067
LifeBio Memory: Development of a Reminiscence Therapy Online Platform With Machine Learning to Increase Engagement
Conditions: Mild Cognitive Impairment
Sex: All
Ages: 60 Years – N/A
Healthy volunteers: Yes
Phase: NA
Enrollment: 168
Sponsor: George Mason University
Summary
LifeBioMEMORY (LBM) is a reminiscence therapy (RT) mobile application that captures older adults' life stories in their own voices to promote social engagement and psychosocial well-being. This study will develop and evaluate an enhanced multilingual LBM app for community-dwelling, diverse older adults with mild cognitive impairment (MCI) or at risk of MCI and their informal caregivers, including Hispanic/Latino, Asian American (as one of subgroups, Korean), Black or African American, and non-Hispanic White populations. The app provides culturally tailored life story prompts with audio and visual cues to encourage reminiscence and storytelling. The intervention aims to improve quality of life, reduce depressive symptoms and loneliness, and strengthen caregiver-care recipient relationships, with the potential to provide an accessible, non-pharmacological approach to supporting cognitive and emotional well-being.
Eligibility Criteria
The investigators will enroll a total of 84 older adult participants and 84 informal caregivers across the 84 dyads, comprising 21 Hispanic/Latino dyads, 21 Korean dyads, 21 Black dyads, and 21 Non-Hispanic White dyads.
The inclusion and exclusion criteria for older adult participants are:
1. Self-identified as Hispanic/Latino, Korean, Black/African American, and Non-Hispanic White
2. Speak and read Spanish, Korean, or English
3. Aged 60 years and older, with Montreal Cognitive Assessment (MoCA) test scores ranging 18-30 (with MCI: 18-25, or at risk for MCI: 26-30)
4. Have a local or in-home informal caregiver who can participate who is age 18 or older
5. No pre-existing acute psychotic disease or critical illness
6. Consent to participate
The inclusion and exclusion criteria for informal caregivers are:
1. Self-identified as Hispanic/Latino, Korean, Black/African American, and Non-Hispanic White
2. Speak and read Spanish, Korean, or English
3. Aged 18 years and older
4. Currently serving as the primary informal caregiver for older adults aged 60 or older
5. No pre-existing acute psychotic disease or critical illness
6. Consent to participate
Source: ClinicalTrials.gov (NCT07685067). StuddyBuddy aggregates publicly available trial information.