Ozone Versus Conventional Socket Disinfection for Primary Dental Implant Stability

This randomized split-mouth controlled clinical trial aims to compare the effects of ozone and conventional implant site disinfection on primary and early secondary implant stability. Systemically healthy adults requiring at least two dental implants in symmetrical or contralateral edentulous sites will receive ozone disinfection at one implant site and conventional disinfection at the paired site according to a randomized allocation. Implant stability will be assessed immediately after implant placement using insertion torque and resonance frequency analysis (Implant Stability Quotient, ISQ), and secondary stability will be evaluated by ISQ measurements at the 3-month follow-up during healing abutment placement. The study will determine whether ozone disinfection improves implant stability during the early osseointegration period.

Inclusion Criteria: * Adults aged 18 years or older. * Systemically healthy individuals requiring at least two dental implants. * Presence of symmetrical or contralateral edentulous sites suitable for dental implant placement. * Adequate bone volume for implant placement without the need for simultaneous bone augmentation. * Ability and willingness to provide written informed consent and comply with the study protocol. Exclusion Criteria: * Adults aged 18 years or older. * Systemically healthy individuals requiring at least two dental implants. * Presence of symmetrical or contralateral edentulous sites suitable for dental implant placement. * Adequate bone volume for implant placement without the need for simultaneous bone augmentation. * Ability and willingness to provide written informed consent and comply with the study protocol.