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Completed
NCT07689006
Real-World Clinical Outcomes in Relapsed/Refractory Multiple Myeloma Treated With Pomalidomide Regimens
Conditions: Relapsed/Refractory Multiple Myeloma
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 341
Sponsor: Bristol-Myers Squibb
Location: OneOncology Network Nashville Tennessee
Summary
This retrospective observational study will use data from the OneOncology United States database to evaluate clinical outcomes in adults with relapsed/refractory multiple myeloma who received pomalidomide-containing or non-pomalidomide-containing treatment as second-line or third-line therapy after prior exposure to lenalidomide and a proteasome inhibitor.
Eligibility Criteria
Inclusion Criteria:
* Have a diagnosis of multiple myeloma (ICD-9: 203.00; ICD-10: C90.0x, C90)
* Are ≥18 years of age at the index date
* Have received a lenalidomide-containing regimen and received a proteasome inhibitor; exposures do not need to occur within the same line of therapy
* Have received ≥1 subsequent lines of therapy after lenalidomide and proteasome inhibitor exposure
* Have received one of the following treatment regimens as the subsequent line (index line) after lenalidomide and proteasome inhibitor exposure:
* Pomalidomide-containing regimens:
* Daratumumab, pomalidomide, and dexamethasone (DPd)
* Carfilzomib, pomalidomide, and dexamethasone (KPd)
* Non-pomalidomide-containing regimens:
* Daratumumab, lenalidomide, and dexamethasone (DRd; lenalidomide-refractory participants only)
* Daratumumab, bortezomib, and dexamethasone (DVd)
* Daratumumab, carfilzomib, and dexamethasone (DKd)
Exclusion Criteria:
* Have \
Source: ClinicalTrials.gov (NCT07689006). StuddyBuddy aggregates publicly available trial information.