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Completed NCT07689006

Real-World Clinical Outcomes in Relapsed/Refractory Multiple Myeloma Treated With Pomalidomide Regimens

Conditions: Relapsed/Refractory Multiple Myeloma

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 341
Sponsor: Bristol-Myers Squibb

Location: OneOncology Network Nashville Tennessee

Summary

This retrospective observational study will use data from the OneOncology United States database to evaluate clinical outcomes in adults with relapsed/refractory multiple myeloma who received pomalidomide-containing or non-pomalidomide-containing treatment as second-line or third-line therapy after prior exposure to lenalidomide and a proteasome inhibitor.

Eligibility Criteria

Inclusion Criteria: * Have a diagnosis of multiple myeloma (ICD-9: 203.00; ICD-10: C90.0x, C90) * Are ≥18 years of age at the index date * Have received a lenalidomide-containing regimen and received a proteasome inhibitor; exposures do not need to occur within the same line of therapy * Have received ≥1 subsequent lines of therapy after lenalidomide and proteasome inhibitor exposure * Have received one of the following treatment regimens as the subsequent line (index line) after lenalidomide and proteasome inhibitor exposure: * Pomalidomide-containing regimens: * Daratumumab, pomalidomide, and dexamethasone (DPd) * Carfilzomib, pomalidomide, and dexamethasone (KPd) * Non-pomalidomide-containing regimens: * Daratumumab, lenalidomide, and dexamethasone (DRd; lenalidomide-refractory participants only) * Daratumumab, bortezomib, and dexamethasone (DVd) * Daratumumab, carfilzomib, and dexamethasone (DKd) Exclusion Criteria: * Have \

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Source: ClinicalTrials.gov (NCT07689006). StuddyBuddy aggregates publicly available trial information.