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NCT07689162
Liposomal Bupivacaine vs Standard Bupivacaine for Post-Rhinoplasty Analgesia
Conditions: Pain, Postoperative
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: PHASE2
Enrollment: 45
Sponsor: Washington University School of Medicine
Location: Washington University St Louis Missouri
Summary
The purpose of this study is to find out which pain medication is more effective in reducing pain after nose surgery (rhinoplasty). The investigators are looking to find the best treatment to reduce discomfort and improve the healing process for patients having nose surgery.
Eligibility Criteria
Inclusion Criteria:
* Adult patients (≥18 years) undergoing open rhinoplasty of any indication or complexity (e.g., primary, revision, functional, or cosmetic), including autologous grafting of any type (e.g., septal or costal cartilage) or cadaveric grafting.
Exclusion Criteria:
* Chronic pain condition requiring ongoing or scheduled analgesic therapy, or any diagnosis associated with chronic pain (e.g., fibromyalgia, chronic headache/migraine, neuropathic pain, complex regional pain syndrome), long-term opioid use (≥3 months, any agent), allergy or contraindication to local anesthetics, acetaminophen, ibuprofen / NSAIDs, tramadol, ketamine, Medrol (methylprednisolone) dose pack
* Concurrent non-nasal surgery planned
Source: ClinicalTrials.gov (NCT07689162). StuddyBuddy aggregates publicly available trial information.