Mild Cognitive Impairment and Neuromodulation

Sex: All

Ages: 55 Years – 80 Years

Healthy volunteers: No

Phase: NA

Enrollment: 40

Sponsor: Virginia Polytechnic Institute and State University

Summary

This is a parallel, sham-controlled design of low-intensity focused ultrasound in patients with mild cognitive impairment (MCI). The study will evaluate safety, tolerability, and effects on cognitive function.

Eligibility Criteria

Inclusion Criteria: * Montreal Cognitive Assessment (MoCA) scores between 18-23 inclusive, and able to consent to their own medical care. Exclusion Criteria: * Claustrophobia * MRI contraindications (pacemaker, aneurysm clips, neurostimulators, cochlear implants, metal in eyes, or other implants) * CT contraindications (pregnancy) * Non-AD etiology (eg. Lewy body disease, vascular dementia, alcohol/drug related damage) * Taking anti-amyloid antibodies * Neuromod within 6 months of the study * History of other neurological disorder * Hx of head injury with LOC \> 10 min * Active alcohol or drug dependence

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT07691918). StuddyBuddy aggregates publicly available trial information.